Pathogenesis, Clinical Characteristics, Quality Of Life And Management Approach Among Women With Polycystic Ovary Syndrome (PCOS)
Introduction: PCOS is most common hormonal disturbance affecting 6%-20% of reproductive age women, considered multifaceted with spectrum of conditions including menstrual irregularities, acne, hair loss, obesity and hirsutism. Moreover, PCOS is also the cause of adverse cardiovascular, metabolic, reproductive and psychological approaches for reduction in QOL. This review will help females understand responsible factors for PCOS incidence, its health consequences and management needed. Methodology: The literature reviewed in this narrative article is obtained from various databases such as Google, PubMed, Scopus, and Web of Science using MeSH-compliant keywords including PCOS, Rotterdam criteria, QOL, PCOS management and consulting related books. References from year 2003 to 2021 were assessed and relatable information included. Results: Studies conducted across country reflects high PCOS prevalence and irregular menses, hirsutism, acne, obesity, AN, infertility and negative impact on QoL. Discussion: PCOS females present with reproductive and metabolic manifestations along with potential of several co-morbidities. Stigma associated with PCOS remains neglected global issue. PCOS has significant association with short and long-term health conditions, if untreated, lead complications. The goals of PCOS management are menstrual regularity, hyperandrogenism reduction, infertility management and IR resolution through non-pharmacological and pharmacological approaches. Conclusion: Large scale studies across country are necessary for actual status. Accurate diagnosis at young age is the key factor. Counselling young females should be done to spread awareness and remove stigma for better future.