Relationship of DMFT and Glomerular Filtration Rate in Adults Residing in Shahedieh city, Yazd Province
Author(s): Abdolrahim Davari, Alireza Daneshkazemi, Sanaz Abbasi* and Farzad Ziaei
Abstract
Background and Objectives: Oral health is a strong predictor of general health and the quality of life. Of all systemic diseases, renal disease is the most important cause of morbidity and mortality. Kidneys are among the critical organs for general health. Chronic kidney disease (CKD) occurs following progressive and irreversible destruction of nephrons, which is associated with decreased glomerular filtration rate (GFR), and increased serum Creatinine and blood urea nitrogen (BUN). Studies regarding the oral health status and prevalence of caries in patients with CKD are limited and controversial. Thus, this study aimed to assess the correlation of DMFT and GFR in adults residing in Shahedieh city. Materials and Methods: Information for this study was collected from the Yazd Shahedieh Project conducted on 9000 people. The serum Creatinine level, and age, gender and weight of patients were extracted from the questionnaire designed for the Yazd Shahedieh Project after obtaining a permit. The GFR of each individual was calculated using the Cockcroft Gault formula. For assessment of oral health status, the DMF index of permanent teeth of adults was calculated. The total number of decayed (D) (dental caries with/without restoration), missing (M) and filled (F) teeth (temporary or permanent filling, or partial filling without caries) was recorded as the DMF index. Data were coded and analyzed using SPSS version 23 via descriptive statistics, t-test, ANOVA, Pearson’s correlation coefficient, and regression analysis. Results: The correlation test showed that weight had no significant correlation with the number of carious teeth (D) but was significantly correlated with the number of filled teeth (F). Also, weight had an inverse correlation with the number of missing (M) teeth and DMFT. Serum Creatinine had no significant correlation with the number of decayed teeth (D) but had a direct correlation with the number of missing teeth (M) and DMFT. Serum Creatinine had an inverse correlation with the number of filled teeth (F). Age had an inverse correlation with the number of decayed (D) and filled (F) teeth but had a direct correlation with the number of missing (M) teeth and DMFT. GFR had a direct correlation with the number of decayed (D) and filled (F) teeth but had an inverse correlation with the number of missing (M) teeth and DMFT. The regression analysis showed that GFR had a significant inverse correlation with DMFT. Conclusion: DMFT had a significant inverse correlation with GFR, and a significant direct correlation with serum Creatinine. Patients with lower GFR and higher serum Creatinine (indicative of higher stage of CKD), had higher DMFT index.