Abubucker Peer Mohideen

Department of Basic Medical Sciences, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj,, Saudi Arabia


  • Research   
    Controlling Multidrug-Resistant (MDR) Infections Using Leucas aspera: In Silico Identification of Phytocompounds Inhibiting DNA Gyrase and Tyrosyl-tRNA Synthetase
    Author(s): Abubucker Peer Mohideen*

    The on-going issue of multidrug resistance (MDR) among bacterial pathogens worldwide has got further worsened during the pandemic COVID-19. The drug-resistant mechanisms evolved by pathogens have disabled the functions of most antibiotics, and the bacteria use several mechanisms in overcoming the effect of antibiotics. MDR infections are so severe that they cause longer morbidity and, left untreated, may lead to the death of the infected. This scenario brings about the necessity for the development of novel antimicrobial drugs from various sources. Since time unknown, different plants and plant materials have been used for the treatment of many of the dreaded infections. Therefore, the present study focuses on the identification of phytochemical compounds present in Leucas aspera that inhibit the antibacterial targets responsible for replication. Phytocompounds present in Leucas asper.. Read More»

    Abstract HTML PDF