C Naveen Kumar
Department of Microbiology, Sri Lakshmi Narayana Institute of Medical Sciences affiliated to Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, IndiaPublications
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Research
Phytochemical Analysis, Antioxidant and Anti-Diabetic Activity of Sargassum wightii (A Marine Alga)
Author(s): Sangiya K and C Naveen Kumar*
The edible seaweed, Sargassum wightii, was investigated for its anti-diabetic potential through in vitro enzyme inhibitory assays. Among the various extracts, extracts of petroleum ether and Syl ethyl acetate. Wightii showed significant inhibitory effects against α-amylase. Methanol extract for S. wightii showed very high inhibition against dipeptidyl peptidase and moderate antioxidant activity was observed in the release of acetone S. wightii. Similarly, the hexyen extract of S. polycystum showed very high inhibition against α-amylase and S-extract methanol. Polycystum inhibition significantly against α-glycosidase as well. The antioxidant activity was negative. Exit was investigated with in vitro cytotoxicity, DNA fragmentation in macrophages and hemolytic activity against erythrocytes, but no significant toxicity was detected by any of the extracts. Gas chromatogr.. Read More»