Gayathri R

Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India


  • Research   
    Effect of Lupeol on Pro-Inflammatory Markers in Adipose Tissue of High-Fat Diet and Sucrose Induced Type-2 Diabetic Rats
    Author(s): Mithil Vora, V Vishnu Priya*, J Selvaraj, Gayathri R and Kavitha S

    Background: Lupeol also called Fagarsterol is found in white cabbage, green pepper and strawberry. It is reported to have beneficial effects for various disorders. However, the mechanisms by which lupeol controls proinflammation-mediated signalling is obscure. Aim: The study was aimed at assessing the effect of lupeol on the expression of proinflammatory signalling molecules antidiabetic activity of lupeol through the expression of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in adipose tissue of high fat diet-induced type-2 experimental rats. Materials and methods: Male Albino Wistar rats were used for the present study and divided into 4 groups of 6 animals each. Group 1: Served as normal control rats; Group II: Serves as high fat diet-induced type-2 diabetic rats; Group III: Diabetic rats treated with Lupeol (25 mg/kg b.wt) and Group IV: Diabetic administere.. Read More»

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