Ponnuswamy Karkuzhali

Sree Balaji Medical College & Hospital Affiliated to Bharath Institute of Higher Education and Research, India

Publications

  • Research   
    Expression of Immunohistochemical Markers in Papillary Carcinoma Thyroid and Non-Neoplastic Lesions of Thyroid
    Author(s): Gayathri Priyadarshini RS and Ponnuswamy Karkuzhali*

    Thyroid gland nodules and carcinoma is extremely common worldwide and are discovered during routine medical care. The most common carcinoma are well- differentiated papillary carcinoma (80% of all thyroid cancers) and follicular carcinoma (15%). The final diagnosis to distinguish cytologically undetermined tumors is made on surgically removed specimen by histopathological examination in routine Hematoxylin-Eosin (H&E) stained sections. Though in many cases diagnosis is obvious by Cytology alone in a sizeable number the diagnosis is only presumptive. PTC has a papillary architecture and distinctive set of nuclear features, such as ground glass nuclei, nuclear grooves and nuclear pseudoinclusions. None of these findings are individually specific totally for Papillary carcinoma. The present study was designed to study the expression of Immunohistochemical markers like ck19, and galec.. Read More»

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