Puneet Fulzele

Department of Oral Pathology, Sharad Pawar Dental College, Wardha, Maharashtra, India


  • Review Article   
    Role of Stem Cells in Oral Cancer
    Author(s): Swati Patil*, Aishwarya Gandhewar, Amit Reche, Kumar Gaurav Chhabra, Puneet Fulzele, Pavan Bajaj and Priyanka Paul Madhu

    Cancer stem cells have been discovered in squamous cell carcinoma of the oral cavity. In oral cancer, cancer stem cells play a crucial role in tumour development, as well as increased recurrences, acquired treatment resistance, and metastasis. Cancer stem cells have the ability to self-renew and multiply forever, producing progenitor cells and cancer cells that feed tumor growth. Many cancers, including oral cavity squamous cell carcinoma, have been identified as cancer stem cells using specific markers, albeit it's still unclear where these markers fit into the stem cell hierarchy. In the development of cancer, the tumor microenvironment exerts a great deal of pressure. The significance of stem cells in mouth cancer was examined in this article. This is confounded by the presence of many CSC subtypes within OCSCC, which makes the study mo.. Read More»

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