R Muthu Kumaran

Director, Dr. Kumaran Multispeciality Hospital, Puducherry, India, India


  • Research   
    Ondansetron Attenuates Hypotension Due To Subarachnoid Block-A Randomised Double Blind, Placebo-Controlled Study
    Author(s): Hemanatha Kannan M, Vijayakumar M Heggeri* and R Muthu Kumaran

    Background: A decrease in arterial blood pressure is one of the known complications of subarachnoid block (SAB) and represents a major cause of concern in some patients. Improvements in surgical and anaesthetic techniques have not helped to curb the incidence of hypotension. Therefore search is going on for various modalities to decrease the incidence. Aim: To test the hypothesis that ondansetron attenuates the arterial hypotension and bradycardia produced due to subarachnoid block. Methods: A randomised double blind, placebo-controlled study was performed on 60 patients. They were divided into two groups. Group O patients received 8 mg ondansetron in 10 ml of isotonic NaCl intravenously before SAB. Group P patients had received isotonic NaCl solution 10 ml intravenously without any added medication before SAB. The systolic (SBP), diastolic (DBP) and mean arterial pressure (MAP) and h.. Read More»

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