R Priyadarshini

Department of Pathology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India


  • Research   
    Clinico Pathological Correlation of Salivary TNF-Alpha Level in Hypertensive Patients under Treatment
    Author(s): Anushya P, Palati Sinduja*, Selvaraj Jayaraman and R Priyadarshini

    Background: TNF- alpha is the key pro-inflammatory cytokines and plays a vital role in the progress of hypertension. At present, hypertensive patients are under treatment with Angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, or diuretics. Recent literature revealed that TNF-alpha levels were suppressed in chronic renal failure and congestive heart failure after treatment with amlodipine and captopril. Aim: The aim of this current study is to determine whether there is any correlation of levels of salivary TNF- alpha level in hypertension along with the action of Calcium channel blockers and ACE inhibitors. Materials and methods: A cross-sectional pilot study in 10 patients with confirmed hypertension. They were categorized into two study groups namely ACE inhibitors and Calcium channel blockers based on their treatment. The salivary samples were collected in a.. Read More»

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