Shamam Kanaan M Abdlkareem

Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad, Iraq


  • Review Article   
    Assessment the Cytotoxic Effect and Phytochemical Constituents of Ethyl Acetate Fraction of Iraqi Cassia glauca on Esophagus Cancer Cells
    Author(s): Shamam Kanaan M Abdlkareem* and Enas Jawad Kadhim

    Background: Cell lines obtained from cancer cells are usually used in experiments, such as use as a representative to cancer and to come up with a new treatment. The aim of the study: To explore the chemical constituents and assessment the anticancer activity against esophageal adenocarcinoma cell line of Cassia glauca (steams, leaves, flowers) parts where no phytochemical study had been done in Iraq on this plant. Method: (Steams, leaves, flowers) parts of C. glauca defatted by maceration in n-hexane. The defatted plant parts were extracted by cold method, the aqueous ethanol 85% used as a solvent for extraction and the extract fractionated by chloroform, ethyl acetate and n-butanol. The ethyl acetate fraction then analyzed by High Performance Liquid Chromatography (HPLC) to investigate its constituents. The MTT assay used.. Read More»

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