Sumaya Mohammed Mansor
Department of Oral Diagnosis, College of Dentistry, University of Baghdad, IraqPublications
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Research
Clinicopathological and Immunohistochemical Comparison of Peripheral and Central Giant Cell Granuloma of the Jaws Using CD68 and CD 163
Author(s): Sumaya Mohammed Mansor* and Ban F Al-drobie
Background: A tumor-like disease that affects the jawbone may develop either peripherally in the periodontal ligament and muco periosteum, peripheral giant cell granuloma (PGCG) or centrally in the bone “central giant cell granuloma” (CGCG). Objectives: To evaluate the expression of CD68 and CD163 proteins in mononuclear cells and compare it between (CGCG) and (PGCG), in addition, to calculate to determine whether or not their expression levels may be utilized to distinguish amongst one another. Methods: In order to conduct this study, we obtained 30 formalin-fixed paraffin-embedded tissue blocks from the archives of the oral pathology laboratory of the oral diagnostic department at the College of Dentistry/University of Baghdad/, with 15 for CGCG and 15 for the PGCG. Four- µm thick sections were cut from the blocks; one section was stained by eosin and hematoxylin f.. Read More»