Serpil Karaoglanoglu

Department of Restorative Dental Treatment, Gulhane Faculty of Dentistry, University of Health Sciences, Ankara, Turkey


  • Research   
    Evaluating Cytotoxic Effects of Resin Based CAD/CAM Blocks
    Author(s): Numan Aydın*, Serpil Karaoglanoglu and Elif Aybala Oktay

    Background: The effects of CAD/CAM blocks containing resin on oral cells, which are widely used in the restoration of teeth recently, are unknown. The aim of this study is in vitro examination of cytotoxic effect of resin and ZLS (zirconia-reinforced lithium silicate) including CAD/CAM blocks on human gingival keratinocyte (HGK) cells. Material and Methods: In our study; samples were prepared (1.5 × 7 × 12 mm) under water cooling, using CAD/CAM blocks. Both surfaces of the prepared samples were polished using a diamond polishing kit (Clearfil Twist Dia, Kururay). Samples, whose surface (3 cm2/ml) were calculated according to the International Standards Organization (ISO 10993-12: 2012), were left for 1, 3- and 7-days incubation in DMEM. Cell viability of extracts of 1:1 ratio of filtered CAD/CAM blocks were examined by MTT test. .. Read More»

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