Shaykhova Munira Ikramovna
Tashkent Pediatric Medical Institute, Tashkent, UzbekistanPublications
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Research
Cause-Effective Relations between Vegetative Status and Inflammation Factors in the Formation of Essential Arterial Hypertension in Children
Author(s): Agzamova Shoira Abdusalamovna*, Akhmedova Firuza Mirzakirovna, Makhkamova Gulnoza Turaxodjaevna and Shaykhova Munira Ikramovna
Study of causal relationships between vegetative status and inflammatory factors (highly sensitive C-reactive protein (CRPhs), tumor necrosis factor-alpha (TNF-α) and anti-inflammatory interleukin-10 (IL-10) in the formation of essential arterial hypertension in children established the heterogeneity of the ergo- and trophotropic effects of the autonomic nervous system on the activity of pro- and anti-inflammatory cytokines and the level of cortisol. The clinical course of essential arterial hypertension in children is manifested by functional abnormalities, tense functioning of the autonomic nervous system, subclinical inflammation with an increase in the level of TNF-α, CRP-hs and a decrease in IL-10, which has features depending on the form of essential arterial hypertension. Increased secretion of cortisol in the group of children with arterial hypert.. Read More»